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Beyond that, desensitization is inevitable

Epigenetic regulation of established human type 1 versus type 2 cytokine responses

In the brains of Alzheimers disease (AD) patients, pathological features such as reduced mitochondrial membrane potential (m), accumulation of mitochondrial peroxides, aberrant opening of the mitochondrial permeability transition pore (mPTP), and mitochondrial iron (mFe) overload are commonly observedeach closely linked to ferroptosis induction (Chen et al., 2023

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